|
KMID : 1023520100330020173
|
|
Korean Journal of Veterinary Service
2010 Volume.33 No. 2 p.173 ~ p.176
|
|
|
Application of chitosan resin formulae as a sustained-releasing form adjuvant
|
|
Kim Sang-Uk
Kang Mun-Il
Lee Jae-Il
Kim Tae-Jung
|
|
|
Abstract
|
|
|
|
Here, we report the suitability of using a resin-type chitosan formulae as a sustained-releasing form adjuvant in comparison with commercially well-known Freund’s adjuvants. To induce the immunological responses, N-terminal region of Pasteurella multocida toxin was used as an antigen, which was found to be protective immunogen against P. multocida infection. Mice immunized with chitosan resin formulae showed statistically significant antibody induction (P<0.001) as much as that of Freund’s adjuvants. As a result, the resin-type sustained-releasing form chitosan formulae is thought to be a good candidate for a new type adjuvant.
|
|
|
KEYWORD
|
|
|
Chitosan, Adjuvant, Pasteurella multocida toxin (PMT), Sustained-release
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|