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KMID : 1023520180410010041
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Korean Journal of Veterinary Service
2018 Volume.41 No. 1 p.41 ~ p.45
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Intestinal T cell lymphoma in a cat, Korea
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Jeong Ji-Yeon
Lee Kyung-Hyun
Choi Eun-Jin
Kim Ji-Hyeon
So Byung-Jae
Lee Seung-Hee
Shin Hyun-Ho
Jung Ji-Youl
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Abstract
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An 11 year-old male Korean short-haired cat was presented to local animal hospital due to weight loss, vomiting, and intestinal hypomotility. After the cat was euthanized by poor clinical outcomes, necropsy was performed at Animal and Plant Quarantine Agency. At necropsy, the stomach was enlarged and had some nearly complete pellet food and the yellow mucous contents. The lumen of the middle and lower parts of the jejunum became narrow. Histopathologically, medium-sized lymphoid cells with hyperchromatic nuclei enclosed by scant cytoplasm were diffusely proliferated from mucosa to serosa of the small intestine. These findings were mainly observed in the jejunum and slightly in the duodenum and ileum. The monomorphous lymphocytes were 1 to 1.5 times larger than red blood cells and had few mitotic figures. Metastasis of the tumor cells to other organs was not observed. In the result of immunohistochemical analysis for identifying the origin of tumor cells, CD3 was expressed, but CD79 was not detected in the infiltrated cells. This case was diagnosed as T cell intestinal lymphoma in a Korean short-haired cat based on the clinical signs, gross findings, histopathology, and immunohistochemistry.
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KEYWORD
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Intestinal lymphoma, Cat, Immunohistochemistry, T lymphocyte, CD3
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