|
KMID : 1023520220450030229
|
|
Korean Journal of Veterinary Service
2022 Volume.45 No. 3 p.229 ~ p.236
|
|
|
Monitoring for fluoroquinolones residues in raw meat in Sejong
|
|
Jeong Yoon-Kyung
Lee Tae-Ho
Lee Jong-Hoon
Kim Mun-Bae
|
|
|
Abstract
|
|
|
|
This study describes an analytical method based on LC-MS/MS for the quantitation of 5 fluoroquinolones (Enrofloxacin, Ciprofloxacin, Marbofloxacin, Norfloxacin and Danofloxacin) in meat, and was applied to 230 meat samples for validation. Quantitation was performed based on a matrix-matched calibration to compensate for the matrix effect on the electrospray ionization. Good linear calibrations (R2≥0.998) were obtained for all fluoroquinolones at 6 concentrations of 1~50 ㎍/kg. Satisfied recoveries of all fluoroquinolones were demonstrated in spiked meat at three levels from 10 to 50 ㎍/kg. The recoveries ranged between 75.8~99.2% in beef, 80.1~99.6% in pork and 72.2~99.8% in chicken, respectively. The limits of quantitation (LOQs) for fluoroquinolones ranged from 0.7 to 3.2 ㎍/kg. We also monitored fluoroquinolones residue in the sample (beef 107, pork 71, chicken 52) using LC-MS/MS. Residues of fluoroquinolones which exceeded maximum residue limits (MRL) were not exceed in any of the 230 samples.
|
|
|
KEYWORD
|
|
|
Fluoroquinolones, Residue, LC-MS/MS, Law meat, Sejong
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|