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KMID : 1024620070270040538
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Food Science of Animal Resources
2007 Volume.27 No. 4 p.538 ~ p.542
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Inhibitory Effect on Rotavirus by Exopolysaccharides Extracted from Kefir
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Song Jin-Ook
Kim Tae-Jin
Kim Yong-Hui
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Abstract
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This study was carried out to investigate the toxicity of exopolysaccharides (EPS) from kefir toward MA104 cells and evaluate the inhibitory effects of kefir EPS on rotavirus infection. The results obtained are summarized as follows: Lactic acid bacteria (Lactobacillus fermentum, L. acidophilus, L. brevis) and yeasts (Candida kefyr, Cryptococcus albidus, Pichia ohmeri) were isolated and identified from kefir grain and culture. At 1% EPS, the inhibitory effects of EPS on the infection of MA-104 cells using the MTT assay were for human rotavirus (KU), for bovine rotavirus (NCDV), and for porcine rotavirus (OSU). At 1/128% EPS, the effects were for human rotavirus (KU), for bovine rotavirus (NCDV), and forporcine rotavirus (OSU). EPS isolated from kefir have inhibitory effects on rotaviruses of various serotypes and rotaviruses from different animals.
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KEYWORD
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kefir, exopolysaccharide (EPS), rotavirus, MTT assay
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