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KMID : 1024620080280040431
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Food Science of Animal Resources
2008 Volume.28 No. 4 p.431 ~ p.436
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Neuroprotective Effects and Physicochemical Characteristics of Milk Fortified with Fibroin BF-7
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Choi Gooi-Hun
Jo Mi-Na
Moon Sun-Hee
Lim Sung-Min
Jung A-Ram
Yoon Yoh-Chang
Paik Hyun-Dong
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Abstract
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The impact of storage on the neuroprotective effects against -induced cell death and physicochemical characteristics of milk fortified with BF-7 were investigated. The BF-7 milk exerted protection of neuronal cells SK-N-SH from amyloid beta ()-induced neuronal stress. Our results showed that incubation of the cell with pretreated BF-7 milk, significantly attenuated apoptotic stress by , considered in cell morphology and nucleus shape. The general compositions were maintained consistently in BF-7 fortified milk (BF-7 milk). The BF-7 did not make any disturbance on pH and titratable acidity. The color change was not detected, either. Also, any microorganism had not been detected with more than 7 days storage at . In sensory evaluation study. the average scores of each sensory attribute were quite similar with plain milk. In conclusion, our results strongly indicate that BF-7 characteristics are quite adequate to be included in milk and BF-7 milk is still working well on neuro-protection, result in enforcing our brain and delaying neurodegeneration.
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KEYWORD
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BF-7, nutraceutical substance, milk, neuroprotective effect, amyloid -peptide
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