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KMID : 1034820090050010075
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Molecular & Cellular Toxicology
2009 Volume.5 No. 1 p.75 ~ p.82
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The Food Safety of Superfine Saengshik Processed by Top-down Technique in Mice
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Kim Dong-Heui
Song Soon-Bong
Qi Xu-Feng
Kang Wie-Soo
Jeong Yeon-Ho
Teng Yung-Chien
Lee Seon-Goo
Kim Soo-Kie
Lee Kyu-Jae
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Abstract
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Saengshik is an uncooked and powdered functional food composed of various edible plants, and has been consumed widely due to its health benefits and convenient uptake. Recently, superfine ground saengshik, which contains a certain extent of nanoscale particles, has been commercialized to enhance efficacy, but its safety has not been determined. This study was conducted to evaluate the food safety of superfine saengshik (SS) through general toxicity examination after oral uptake in mice compared to conventional fine saengshik (FS). The SS particle size distribution was 0.479-26.303 f.1m in diameter, with about 68.92% of particles with a diameter < . From our safety evaluation, the number of white blood cells (WBCs) and biochemical values in the serum fell into the normal range, and the weight of organs showed no significant difference between FS and SS groups. Histological observation of the liver, small intestine and large intestine did not show any abnormal or pathological findings under light microscopy. Our results suggest that oral intake of SS is not harmful to mice in terms of general toxicity.
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KEYWORD
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Nanomill, Food safety, Saengshik, Superfine
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