|
KMID : 1034820210170020151
|
|
Molecular & Cellular Toxicology
2021 Volume.17 No. 2 p.151 ~ p.160
|
|
|
The effect of cyfluthrin on testis inhibin B in rats and the intervention of Lycium barbarum polysaccharide
|
|
Guo Xin
Xie Yong-Xin
Guo Chen
Wei Jing-Lin
Yang Hui-Fang
|
|
|
Abstract
|
|
|
Background: In recent years, studies have shown that cyfluthrin is harmful to the reproductive system. Lycium barbarum polysaccharide may be a protective agent.
Objective: To investigate the effect of cyfluthrin (Cy) on testosterone B (inhibin B, INHB) in male rats and the intervention of Lycium barbarum polysaccharide (LBP).
Results: Compared with the control group, the mRNA and protein expression levels of INH α and INH βB in the testis tissue decreased, and the difference was statistically significant (P?
Conclusion: The decrease of INHα and INHβB expression caused by Cy exposure indicates that Cy has a toxic effect on the testis of rats, and the addition of LBP has a certain protective effect on the testis of rats.
|
|
|
KEYWORD
|
|
|
Cyfluthrin, Rats, Testis Inhibin B, Lycium barbarum polysaccharide
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|