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KMID : 1034820220180020159
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Molecular & Cellular Toxicology
2022 Volume.18 No. 2 p.159 ~ p.163
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Relationship between the levels of cord blood resistin, adiponectin, CD4 and CD8 and their influence on early neonatal outcomes
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Wang Na
Li Tiezhi
Hao Ling
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Abstract
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Background: To explore the relationship between neonatal cord blood resistin, adiponectin, CD4 and CD8 and their influence on early neonatal outcomes.
Objective: A total of 150 newborns delivered at term were selected as subjects to detect the levels of cord blood resistin, adiponectin, CD4 and CD8. The cases of neonatal asphyxia, respiratory distress, macrosomia and amniotic fluid inhalation syndrome were recorded.
Results: There were 6 cases of high CD4 and 7 cases of low CD8 among the 150 newborns. There were 10 cases of macrosomia and 5 cases of respiratory distress. According to Pearson correlation analysis, there was no statistically significant difference in cord blood resistin between CD4 and CD8 in newborns delivered at term (r?=?0.132, r?=?0.098, P?>?0.05). There was no significant difference between adiponectin, CD4 and CD8 (r?=?0.104, r?=?0.107, P?>?0.05). There were 10 cases of macrosomia and 5 cases of respiratory distress in newborns, and there were no newborns with amniotic fluid inhalation syndrome and asphyxia. According to Pearson correlation analysis, cord blood resistin was negatively correlated with the body weight of large newborns and the level of neonatal respiratory distress (r?=?? 0.542, r?=?? 0.467, P?
Conclusion: The level of cord blood resistin and adiponectin can measure fetal growth and development, and are closely related to neonatal early outcomes.
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KEYWORD
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Newborn, Resistin, Adiponectin, CD4, CD8, Neonatal outcome
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