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KMID : 1034920090020010001
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Journal Of Oriental Pharmacy
2009 Volume.2 No. 1 p.1 ~ p.5
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Inhibitory effect of Butanol fraction of Ecklonia cava on inflammatory mediators in RAW 264.7 cells
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Chae Hee-Sung
Choi Jang-Ki
Kwon Dong-Yeul
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Abstract
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Objectives : The purpose of this study was to investigate the anti-inflammatory effects of Ecklonia cava butanol extract (BFEC) on RAW 264.7 cells. Method : To evaluate of anti-inflammatory of BFEC, We examined cytokine and Nitric oxide(NO) production in lipopolysacchride (LPS)-induced RAW 264.7 cell. Result : Extract of BFEC inhibit LPS-induced interleukin (IL)-6, NO production in human monocyte RAW 264.7 cells. Conclusion : BFEC down-regulated LPS-induced IL-6, NO production, which may be provide a clinical basis for anti-inflammatory properities of BFEC.
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KEYWORD
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Ecklonia cava butanol extract (BFEC), anti-inflammation, interleukin (IL)-6, Nitric oxide(NO)
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