|
KMID : 1034920090020010033
|
|
Journal Of Oriental Pharmacy
2009 Volume.2 No. 1 p.33 ~ p.42
|
|
|
Effects of Yeonlyeonggobon-dan on the Accumulation Toxicity of As in Organs of Rats
|
|
Lim Jong-Pil
Lee Hong-Kyu
|
|
|
Abstract
|
|
|
|
Sodium arsenate and Yeonlyeonggobon-dan (nianlinggubendan) extract, a herbal restorative were treated p.o. 20mg/kg and 500mg/kg respectively and concurrently to rats, and examined the variation of the body weight and the accumulation of arsenic in organs. Yeonlyeonggobon-dan (nianlinggubendan) extract(YGD) resulted in the increase of body weight, and the increase ratio of body weight in arsenic-treated group was dropped but the group of concurrent administration with YGD showed significant recovery. The ratio of liver weight / body weight of arsenic-treated group increased but the group of concurrent administration with YGD showed significant decrease. The accumulation of arsenic in liver and kidney of arsenic-treated group increased but the group of concurrent administration with YGD showed significant decrease.
|
|
|
KEYWORD
|
|
|
Yeonlyeonggobon-dan (nianlinggubendan), sodium arsenate, accumulation
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|