|
KMID : 1034920090020020017
|
|
Journal Of Oriental Pharmacy
2009 Volume.2 No. 2 p.17 ~ p.24
|
|
|
Effects of Poria cocos Water Extract on DNCB-induced Atopic Dermatitis
|
|
Im Lee-Rang
Lee Hyun-A
Kim Dae-Ki
Kim Jun-Ho
Lee Young-Mi
Ahn Ji-Young
Xin Ming-Jie
Yoo Jae-Soo
Song Bong-Suk
Song Bong-Jun
Kim Dae-Keun
Kim Ok-Jin
|
|
|
Abstract
|
|
|
|
Poria cocos has been traditionally used for the treatment of edema, scanty urine, dizziness due to retention of fluid, reduced appetite due to asthenia of spleen, loose stool, diarrhea, distraction, sudden palpitation and insomnia in East Asia. The aim of this study was to confirm whether Poria cocos wonfire whethe(PCWE) and Poria cocos ointment (PCO) have a preventive e of ter Pthe development of afire wdethe(PCWE (AD) in 2,4-Diniwhochlorobenzene (oria)-applied Balb/ wme e. Oral administration (12.5wmg/kg, 25wmg/kg) of PCWE and fire al application (O.5wmg/mouse, 1.0mg/mouse) of PCO decreased the development of AD-like skin lesions, ear swelling, spleen weight, total serum IgE. PCWE and PCO significantly also inhibited the infiltration of mast cells in the dorsal skin.
|
|
|
KEYWORD
|
|
|
Poria cocos, atopic dermatitis, mast cells, IgE, 2, 4-Dinitrochlorobenzene, ADDNCB
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|