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KMID : 1035520230110010066
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Brain Tumor Research and Treatment
2023 Volume.11 No. 1 p.66 ~ p.72
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A Rare Occurrence of Primarily Extranodal Spinal Epidural Lymphoma With Spinal Cord Compression and Invasion to the Thoracic Cavity
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Seok Min-Cheol
Madadi Ahmad Khalid
Mosleh Mohammad Mohsen
Chang Sun-Hee
Sohn Moon-Jun
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Abstract
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A 41-year-old man suffered from progressive radiculomyelopathy caused by spinal epidural mass primarily encasing the spinal cord at the cervicothoracic vertebrae that extended into the thoracic cavity through the neural foramen. An urgent decompressive laminectomy and epidural tumor resection were performed to prevent neurological deterioration and effective spinal cord decompression. The histopathologic diagnosis was diffuse large B-cell lymphoma. As first-line treatment for stage II extranodal lymphoma, he received 6 cycles of R-CHOP (rituximab/cyclophosphamide, hydroxydaunorubicin, Oncovin, and prednisone) chemotherapy. Consequently, follow-up positron-emission tomography CT and MR images demonstrated a complete metabolic response (Deauville score 1). This rare occurrence of primarily extranodal spinal epidural lymphoma with limited disease will be presented in a literature review.
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KEYWORD
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Lymphoma, Non-Hodgkin, Diffuse large cell lymphoma, Spinal cord compression, Epidural neoplasms
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