KMID : 1038020160240040157
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Translational and Clinical Pharmacology 2016 Volume.24 No. 4 p.157 ~ p.160
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Absorption and Half-Life
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Holford Nick
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Abstract
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This tutorial deals with basic concepts of absorption processes and links previous tutorials on clearance and volume of distribution to introduce the concept of half-life. The time course of both absorption and elimination are commonly described using a half-life. Half-life can also be used to describe drug accumulation. Understanding the principles underlying the time course of absorption and elimination are essential in pharmacotherapy and clinical pharmacology.
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KEYWORD
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absorption, half-life, pharmacokinetics, clinical pharmacology
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