|
KMID : 1038020170250030114
|
|
Translational and Clinical Pharmacology
2017 Volume.25 No. 3 p.114 ~ p.116
|
|
|
Inhibition of indoxyl sulfate-induced intrarenal renin-angiotensin system activation: targeting the aryl hydrocarbon receptor
|
|
Akbar Muhammad Firman
|
|
|
Abstract
|
|
|
|
Indoxyl sulfate, a protein-bound uremic toxin, leads to CKD (chronic kidney disease) progression and its complications through the activation of AhR (aryl hydrocarbon receptor) and RAS (renin-angiotensin system). Inhibition of these pathways may slow the development of CKD and CKD-associated complications.
|
|
|
KEYWORD
|
|
|
Chronic Kidney Disease, Indoxyl Sulfate, Aryl Hydrocarbon Receptor, Renin-Angiotensin System
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|