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KMID : 1038020170250030125
Translational and Clinical Pharmacology
2017 Volume.25 No. 3 p.125 ~ p.133
Pharmacometric models simulation using NONMEM, Berkeley Madonna and R
Park Wan-Su

Abstract
In this tutorial, we introduce a differential equation simulation model for use in pharmacometrics involving NONMEM, Berkeley Madonna, and R. We report components of the simulation code and similarities/differences between software, rather than how to use each software. Depending on the purpose of the simulation, an appropriate tool can be selected for effective communication.
KEYWORD
NONMEM, Berkeley Madonna, R, Pharmacometrics, Simulation
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