KMID : 1038720140250040210
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Progress in Medical Physics 2014 Volume.25 No. 4 p.210 ~ p.217
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Comparison of Anisotropic Analytic Algorithm Plan and Acuros XB Plan for Lung Stereotactic Ablative Radiotherapy Using Flattening Filter-Free Beams
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Chung Jin-Beom
Eom Keun-Yong Kim In-Ah Kim Jae-Sung Lee Jeong-Woo Hong Se-Mie Park Byung-Moon Kim Yon-Lae Kang Sang-Won Suh Tae-Suk
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Abstract
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This study investigated the dosimetric effects of different dose calculation algorithm for lung stereotactic ablative radiotherapy (SABR) using flattening filter-free (FFF) beams. A total of 10 patients with lung cancer who were treated with SABR were evaluated. All treatment plans were created using an Acuros XB (AXB) of an Eclipse treatment planning system. An additional plans for comparison of different alagorithm recalcuated with anisotropic analytic algorithm (AAA) algorithm. To address both algorithms, the cumulative dose-volume histogram (DVH) was analyzed for the planning target volume (PTV) and organs at risk (OARs). Technical parameters, such as the computation times and total monitor units (MUs), were also evaluated. A comparison analysis of DVHs from these plans revealed the PTV for AXB estimated a higher maximum dose (5.2%) and lower minimum dose (4.2%) than that of the AAA. The highest dose difference observed 7.06% for the PTV V105%. The maximum dose to the lung was also slightly larger in the AXB plans. The percentate volumes of the ipsilateral lung (V5, V10, V20) receiving 5, 10, and 20 Gy were also larger in AXB plans than for AAA plans. However, these parameters were comparable between both AAA and AXB plans for the contralateral lung. The differences of the maximum dose for the spinal cord and heart were also small. The computation time of AXB plans was 13.7% shorter than that of AAA plans. The average MUs were 3.47% larger for AXB plans than for AAA plans. The results of this study suggest that AXB algorithm can provide advantages such as accurate dose calculations and reduced computation time in lung SABR plan using FFF beams, especially for volumetric modulated arc therapy technique.
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KEYWORD
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Anisotropic analytical algorithm, Acuros XB, Stereotactic ablative radiotherapy, Lung cancer
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