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KMID : 1038720180290020073
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Progress in Medical Physics
2018 Volume.29 No. 2 p.73 ~ p.80
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Dosimetric Plan Comparison of Accelerated Partial Breast Irradiation (APBI) Using CyberKnife
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Lee Chang-Yeol
Kim Woo-Chul
Kim Hun-Jeong
Lee Jeong-Shim
Park Seung-Woo
Huh Hyun-Do
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Abstract
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Accelerated partial breast irradiation (APBI) is a new treatment delivery technique that decreases overall treatment time by using higher fractional doses than conventional fractionation. Here, a quantitative analysis study of CyberKnife-based APBI was performed on 10 patients with left-sided breast cancer who had already finished conventional treatment at the Inha University Hospital. Dosimetric parameters for four kinds of treatment plans (3D-CRT, IMRT, VMAT, and CyberKnife) were analyzed and compared with constraints in the NSABP B39/RTOG 0413 protocol and a published CyberKnife-based APBI study. For the 10 patients recruited in this study, all the dosimetric parameters, including target coverage and doses to normal structures, met the NSABP B39/RTOG 0413 protocol. Compared with other treatment plans, a more conformal dose to the target and better dose sparing of critical structures were observed in CyberKnife plans. Accelerated partial breast irradiation via CyberKnife is a suitable treatment delivery technique for partial breast irradiation and offers improvements over external beam APBI techniques.
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KEYWORD
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APBI, Cyberknife, Treatment planning
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