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KMID : 1038820190220040341
Pediatric Gastroenterology, Hepatology & Nutrition
2019 Volume.22 No. 4 p.341 ~ p.349
The Gastroesophageal Reflux Disease Questionnaire in Adolescents: What Is the Best Cutoff Score?
Artanti Dian

Hegar Badriul
Kaswandani Nastiti
Soedjatmiko
Prayitno Ari
Devaera Yoga
Vandenplas Yvan
Abstract
Background: A self-assessment questionnaire, the GERD-Questionnaire (GERD-Q) was used to determine the prevalence of GERD in adolescents, describe the related factors, and determine the impact on quality of life (QoL).

Methods: The incidence of GERD was evaluated using the GERD-Q in adolescents aged 12?18 years. The Pediatric Gastroesophageal Reflux Disease Symptom Questionnaire and Quality of Life Questionnaire (PGSQ-A) for adolescents were additionally administered. Some factors considered related to GERD were also evaluated.

Results: The 520 adolescents were included. The prevalence of suspected GERD, according to a GERD-Q cutoff score of ¡Ã7 was 32.9%, and those drinking soda were 1.7 times more likely to have GERD (95% confidence interval, 1.3?2.2; p<0.001). However, soda consumption was not a risk factor for development of GERD symptoms. Applying a cutoff score of ¡Ã8, only 10.9% of the participants had a positive GERD score, but the association with soda consumption persisted. The median PGSQ-A score in subjects suspected of GERD was 8 (range 0?37) on weekends and 1 (range 0?17) during weekdays (p<0.001) compared to those not suspected of GERD, with a median of 2 (range 0?27) during weekends and 0 (range 0?10) during weekdays. Heartburn, regurgitation, and extraesophageal symptoms correlated significantly with QoL (p<0.001).

Conclusion: The prevalence of suspected GERD in adolescents was 32.9% or 10.9%, depending on the cutoff score used. There was a statistically significant difference in PGSQ-A scores between the subjects suspected or not of GERD, indicating an impaired QoL.
KEYWORD
Gastroesophageal reflux disease, Questionnaire, Quality of life, Adolescent
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