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KMID : 1099620070040030140
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Korean Journal of Spine
2007 Volume.4 No. 3 p.140 ~ p.145
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Clinical Analysis of Newly Developed Vertebral Fractures after Percutaneous Vertebroplasty in Osteoporotic Thoracolumbar Vertebral Compression Fractures
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Park Jin-Gyu
Park Chun-Kun
Ryu Kyeong-Sik
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Abstract
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Objectives: Recently, many clinicians have analyzed the therapeutic effects of polymethylmethacrylate percutaneous vertebroplasty(PMMA-PV) for the treatment of osteoporotic vertebral fractures. However, it has been suggested that PMMA-PV enhances new vertebral fractures in the level adjacent to the previously treated site. The authors verified the clinical relationship between PMMA-PV and newly developed vertebral fractures following this procedure.
Methods: Among 215 patients treated with PMMA-PV, 32 cases(14.9%) experienced newly developed thoraco-lumbar vertebral fractures during the follow-up period(8.9±5.9 months on the average). There were 2 male and 30 female patients. The mean age was 71.3 years. The numbers of previously treated and newly developed vertebrae were 87 and 53, res- pectively. The average amount of injected PMMA during the first operation was 4.41±1.62cc. The average T-score of bone mineral densitometey(BMD) was -2.91±1.26.
Results: Among 53 newly fractured vertebrae, 23(43.4%) were located adjacently to previously treated vertebrae. In statistical analysis between the locations of new fractures and the amount of previously injected PMMA, T-score of BMD did not show any significant relationship.
Conclusion: Our data revealed that new vertebral fractures following PMMA-PV have a tendency to occur at the adja- cent level to be treated previously. The amount of injected PMMA and the T-score of BMD were not related with the location of new fractures.
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KEYWORD
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Osteoporosis, Vertebral fracture, Percutaneous vertebropalsty, Polymethylmethacrylate
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