|
KMID : 1099620160130010024
|
|
Korean Journal of Spine
2016 Volume.13 No. 1 p.24 ~ p.29
|
|
|
The Use Fibrin Sealant after Spinal Intradural Tumor Surgery: Is It Necessary?
|
|
Won Young-Il
Kim Chi-Heon
Chung Chun-Kee
Jahng Tae-Ahn
Park Sung-Bae
|
|
|
Abstract
|
|
|
Objective: A fibrin sealant is commonly applied after closure of an incidental or intended durotomy to reduce the complications associated with the leakage of cerebrospinal fluid. Routine usage might not be essential after closure of an intended durotomy, which has clear cut-margins. We investigated the efficacy of fibrin sealants for primary intradural spinal cord tumor surgery.
Methods: A retrospective review was performed for 231 consecutive surgically treated patients with primary intradural spinal cord tumors without extradural extension. Fibrin sealants were not used for 47 patients (group I: age, 51.57±16.75 years) and were applied to 184 patients (group II: age, 48.8±14.7 years). The surgical procedures were identical except for the use of a fibrin sealant after closure of the durotomy. The primary outcome was the occurrence of complications (wound problems, hematoma collection, infection, and neurological deterioration). The covariates were age, sex, body mass index, operation time, pre-/postoperative ambulation, number of laminectomies, and type of tumor.
Results: Schwannoma was the most common pathology (n=134), followed by meningioma (n=35) and ependymoma (n=31). Complications occurred in 13 patients (3 in group I and 10 in group II, p=0.73). The postoperative ambulation status (p<0.01; odds ratio, 28.8; 95% confidence interval, 6.9-120.0) and operation time (p=0.04; cutoff, 229 minutes; sensitivity, 62%; specificity, 72%) were significant factors, whereas the use of a fibrin glue was not (p=0.47).
Conclusion: The use of a fibrin sealant might not be essential to reduce complications after surgery for primary spinal intradural tumor.
|
|
|
KEYWORD
|
|
|
Fibrin tissue adhesive, Spine, Surgical wound infection, Cerebrospinal fluid, Spinal cord neoplasms
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
 
|
|