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KMID : 1100220050040020097
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Dementia and Neurocognitive Disorders
2005 Volume.4 No. 2 p.97 ~ p.100
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Follow-up Brain MRI Findings in a Patient with Posterior Cortical Atrophy
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Kim Byeong-Chae
Choi Seong-Min
Lee Seung-Han
Park Man-Seok
Kim Myeong-Kyu
Cho Ki-Hyun
Na Duk-Lyul
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Abstract
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Posterior cortical atrophy (PCA) is a rare dementia syndrome with early onset, characterized by cortical visual dysfunction and disproportionate focal atrophy of posterior cortex. A 64-yearold right-handed woman with PCA, who initially presented at age 58 years with visuo-spatial impairment, was followed over a 6-year period. She underwent three serial magnetic resonance (MR) imaging over 5 years and F18-FDG brain positron emission tomography (PET). When her cognitive function deteriorated, cortical atrophy was more severe on the follow-up MRI than on the previous one in the bilateral occipitotemporal areas. Results from F18-FDG brain PET demonstrated bilaterally asymmetric (right greater than left) occipitotemporoparietal hypometabolism. We report a patient with PCA with a focus on serial MR imaging findings. This case supports the progressive and spreading nature of the cortical atrophy from occipital to temporoparietal area on serial brain MRIs.
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KEYWORD
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Posterior cortical atrophy, Magnetic resonance imaging, Positron emission tomography
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