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KMID : 1100220070060010018
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Dementia and Neurocognitive Disorders
2007 Volume.6 No. 1 p.18 ~ p.21
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Reversible Frontal Lobe Dysfunction in a Patient with Extrapontine Myelinolysis
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Ha Sang-Wook
Yoo Bong-Goo
Kim Min-Jeong
Kim Jong-Kuk
Kim Kwang-Soo
Choi Young-Sik
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Abstract
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Extrapontine myelinolysis (EPM) is an acute demyelinating disease caused by rapidly fluctuating serum osmolality. EPM mainly affects the bilateral basal ganglia, such as the caudate nucleus, putamen, and globus pallidus. Its major clinical symptoms are movement disorders such as parkinsonism, dystonia, and catatonia. However, frontal lobe dysfunction, such as executive dysfunction, personality changes, and apathy, is rare. We report a patient with EPM with reversible frontal lobe dysfunction without any definite movement symptoms. EPM should be included in the differential diagnosis when a patient shows acute behavioral changes following correction of electrolyte imbalance.
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KEYWORD
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Extrapontine myelinolysis, Frontal lobe dysfunction, Electrolyte imbalance
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