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KMID : 1100320160330010068
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Yeungnam University Journal of Medicine
2016 Volume.33 No. 1 p.68 ~ p.71
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Tumoral calcinosis and calciphylaxis treated with subtotal parathyroidectomy and sodium thiosulphate
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Cho Hyun-Jeong
Yi Yong-Jin
Kang Eun-Jeong
Park Seok-Woo
Cho Eun-Jin
Cho Sung-Tae
Chun Rho-Won
Lee Kyu-Eun
Oh Kook-Hwan
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Abstract
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Tumoral calcinosis (TC) is a condition resulting from extensive calcium phosphate precipitation, primarily in the periarticular tissues around major joints. Calciphylaxis is a fatal ischemic vasculopathy mainly affecting dermal blood vessels and subcutaneous fat. This syndrome is rare and predominantly occurs in patients with end-stage renal disease. Here, we report on a rare case involving a patient with TC complicated with calciphylaxis. Our patient was a 31-year-old man undergoing hemodialysis who presented with masses on both shoulders and necrotic cutaneous ulcers, which were associated with secondary hyperparathyroidism, on his lower legs. He underwent subtotal parathyroidectomy, and sodium thiosulfate (STS) was administered for 27 weeks. Twenty months after beginning the STS treatment course, he experienced dramatic relief of his TC and calciphylaxis.
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KEYWORD
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Tumoral calcinosis, Calciphylaxis, Parathyroidectomy, Sodium thiosulphate
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