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KMID : 1100320200370020136
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Yeungnam University Journal of Medicine
2020 Volume.37 No. 2 p.136 ~ p.140
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Anti-nuclear antibody-negative immunoglobulin G4-associated autoimmune hepatitis mimicking lymphoproliferative disorders
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Kang Min-Kyu
Park Jung-Gil
Choi Joon-Hyuk
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Abstract
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Immunoglobulin G4 (IgG4)-associated autoimmune hepatitis (AIH) is a very rare subtype of autoimmune hepatitis and characterized by marked elevated serum IgG and hepatic infiltration of IgG4-expressing plasma cells. Pathologic confirmation of hepatic IgG4-expressing plasma cells is usually required for the final diagnosis of IgG4-associated AIH. Herein, we report the case of a 47-year-old female diagnosed with autoantibody-negative IgG4-associated AIH mimicking lymphoproliferative disorders.
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KEYWORD
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Autoimmune hepatitis, Immunoglobulin G, Immunoglobulin G4-related disease, Plasma cells, Prednisolone
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