KMID : 1100820110010010064
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Laboratory Medicine Online 2011 Volume.1 No. 1 p.64 ~ p.66
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A Case of Anti-Sda Proven by Urine Neutralization Test
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Yun Seung-Gyu
Kim Jang-Su Yang Jin-Hyuk Yoon Soo-Young Lee Chang-Kyu Lim Chae-Seung Cho Yun-Jung Kim Young-Kee Lee Kap-No
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Abstract
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Anti-Sda is of no clinical significance, because it rarely causes hemolytic transfusion reactions. Even when its presence is suspected during antibody screening test, further identification of the antibody is usually not performed. We experienced a case of anti-Sda in 73 yr-old male patient showing mixed field agglutination by microcolumn agglutination. Antibody specificity could not be identified by conventional antibody identification test, and it was proven to be anti-Sda by urine neutralization test. In spite of its little clinical significance, it may give incompatible crossmatching results reacting with Sda antigen, which occurs at a high frequency in general population. When incompatible crossmatch results arising from anti-Sda are suspected, the problem may be solved by using the urine-neutralized serum of in crossmatching test.
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KEYWORD
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Anti-Sda, Urine neutralization test, Mixed field agglutination
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