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KMID : 1100820110010010064
Laboratory Medicine Online
2011 Volume.1 No. 1 p.64 ~ p.66
A Case of Anti-Sda Proven by Urine Neutralization Test
Yun Seung-Gyu

Kim Jang-Su
Yang Jin-Hyuk
Yoon Soo-Young
Lee Chang-Kyu
Lim Chae-Seung
Cho Yun-Jung
Kim Young-Kee
Lee Kap-No
Abstract
Anti-Sda is of no clinical significance, because it rarely causes hemolytic transfusion reactions. Even when its presence is suspected during antibody screening test, further identification of the antibody is usually not performed. We experienced a case of anti-Sda in 73 yr-old male patient showing mixed field agglutination by microcolumn agglutination. Antibody specificity could not be identified by conventional antibody identification test, and it was proven to be anti-Sda by urine neutralization test. In spite of its little clinical significance, it may give incompatible crossmatching results reacting with Sda antigen, which occurs at a high frequency in general population. When incompatible crossmatch results arising from anti-Sda are suspected, the problem may be solved by using the urine-neutralized serum of in crossmatching test.
KEYWORD
Anti-Sda, Urine neutralization test, Mixed field agglutination
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