KMID : 1100820140040020071
|
|
Laboratory Medicine Online 2014 Volume.4 No. 2 p.71 ~ p.76
|
|
Comparison of the Characteristics of Patients with diabetes as Diagnosed Using Three Different Tests
|
|
Choi Jae-Hoon
Park Ile-Kyu
|
|
Abstract
|
|
|
Background: Diabetes diagnosis can be made using different laboratory tests, including the fasting plasma glucose (FPG) test, 75-g 2-h oral glucose tolerance test (2-h OGTT), and hemoglobin A1c (HbA1c) test; however, these tests have different meanings. This study aimed at comparing patient characteristics based on the diagnosis using each of these 3 tests.
Methods: A total of 750 adults suspected of having diabetes and aged ¡Ã18 years underwent the following tests on the same day: FPG, 2-h OGTT, HbA1c, insulin, general chemistry, and routine urinalysis. The patients were divided into 8 groups based on the combination of positive and negative results of each of the 3 tests, and the characteristics of the patients were compared among groups.
Results: In the group that tested positive for all 3 tests, the FPG, 2-h OGTT, HbA1c, homeostasis model assessment for insulin resistance, alanine transaminase, triglyceride, and urine glucose positive values were higher than those of the group that tested positive using the 2-h OGTT and HbA1c test. In the group that tested positive using the 2-h OGTT, blood urea nitrogen was higher than that of the group that tested positive using the HbA1c test.
Conclusions: The characteristics of the patients differed between the tests that yielded positive diagnostic results. This may be related to the fact that the 3 tests indicate different states of glucose metabolism. The results of the 3 tests were significantly different; therefore, it may be more effective to combine the results of the 3 tests to comprehensively describe patient characteristics.
|
|
KEYWORD
|
|
Diabetes mellitus, Diagnosis, Difference
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|