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KMID : 1100820230130040308
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Laboratory Medicine Online
2023 Volume.13 No. 4 p.308 ~ p.317
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Evaluation of Two Safety Syringes for Arterial Blood Gas Analysis
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Kim A-Ram
Lee Seung-Hoo
Kim Soll-Ip
Lee Woo-Chang
Chun Sa-Il
Min Won-Ki
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Abstract
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Background : Arterial blood gas (ABG) analysis is a crucial test providing vital information for patients who are critically ill. Accurate results are essential; however, pre-implementation evaluation of ABG syringes is uncommon. We evaluated the performance of the Greenmedi heparin syringe (GRS; SANG-A FRONTEC, Korea) and the Portex arterial blood sampling kit (POS; Smiths Medical, USA), which are widely used in clinical laboratories.
Methods : Samples from Asan Medical Center were assessed for clotting rate and hemolysis rate. Gas permeability, sample volume impact, precision, and concordance were evaluated using quality control materials. Gas permeability was assessed by measuring pO2, pCO2, and pH after storing the materials for different time periods. The influence of sample volume was tested at various quantities. Precision was evaluated through repeated tests, and concordance between the two syringes’ results was analyzed.
Results : GRS had a clotting rate of 1.07% (51/4,769), exceeding the acceptable range, whereas POS had no clotted samples (0/387). Hemolysis rates were 14.9% (14/94) for GRS and 10.0% (8/80) for POS, both higher than the acceptable rate. Both syringes had a storage time of less than 10 minutes and required a minimum sample volume above 0.6 mL. Precision was noteworthy, but there was a relatively weak concordance between pO2 values obtained with the two syringes.
Conclusions : Both syringes demonstrated notable precision but had high hemolysis rates. Results showed low concordance and were influenced by storage time and sample volume. Caution should be exercised when using these syringes, and it is recommended to assess their quality before implementation in each laboratory.
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KEYWORD
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Blood gas analysis, Syringes, Evaluation
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