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KMID : 1100920180390010054
Korean Journal of Family Medicine
2018 Volume.39 No. 1 p.54 ~ p.56
A Case of a Girl with Arnold-Chiari Type 1 Malformation with Precocious Puberty
Kim Min-Sun

Hwang Pyoung-Han
Lee Dae-Yeol
Abstract
A small percentage of individuals have the neurological anomaly of central precocious puberty (CPP). Common neurologic causes of CPP include a tumor or congenital lesions. Although Arnold-Chiari malformation can be caused by congenital or acquired causes, it is unusual in patients with CPP. We present the case of a girl aged 4.5 years who complained of breast budding. Her neurological examination and growth pattern were normal. She had no endocrinological abnormality, except for true precocious puberty. We performed brain magnetic resonance imaging, which showed an Arnold-Chiari type 1 malformation. Currently, this case represents the youngest girl who exhibited both Arnold-Chiari type 1 malformation and precocious puberty. Furthermore, it is likely that there is a meaningful association between the brain lesion and precocious puberty in this case.
KEYWORD
Precocious Puberty, Arnold-Chiari Malformation, Child
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