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KMID : 1101620220330040218
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Perinatology
2022 Volume.33 No. 4 p.218 ~ p.224
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Omphalocele?Exstrophy?Imperforate Anus?Spinal Defect Complex in an Infant from Monozygotic Twins Conceived by In Vitro Fertilization: A Case Report
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Baek Gyeong-Yoon
Cho Hye-Jung
Kim Eun-Jin
Kim Suk-Young
Son Dong-Woo
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Abstract
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The omphalocele?exstrophy?imperforate anus?spinal defect (OEIS) complex is a combination of congenital birth defects. This disease is rare and difficult to diagnose during pregnancy. However, if omphalocele, lumbosacral meningomyelocele, and difficulty in visualizing the bladder are observed on prenatal ultrasonography, the OEIS complex should be suspected. Prenatal diagnosis is important because this disease requires sophisticated multidisciplinary management to avoid excessive morbidity. We report a prenatally suspected case of OEIS complex in a fetus of monozygotic twins conceived by in vitro fertilization, which was later diagnosed after birth with omphalocele, bladder exstrophy, vesicointestinal fistula, imperforate anus, meningomyelocele, and club feet.
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KEYWORD
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Omphalocele exstrophy imperforate anus, Neural tube defects, Urogenital abnormalities, Fertilization in vitro, Infant
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