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KMID : 1104820130010010053
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Journal of Digestive Cancer Research
2013 Volume.1 No. 1 p.53 ~ p.57
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A Case of Complete Remission after Concurrent Chemoradiotherapy for Esophageal Squamous cell Carcinoma with Solitary Bone Metastasis
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Lee Woo-Jin
Chun Hoon-Jai
Kim Ye-Ji
Kim Sun-Young
Seo Min-Ho
Lee Yoon-Taek
Kim Eun-Sun
Keum Bo-Ra
Jeen Yoon-Tae
Lee Hong-Sik
Um Soon-Ho
Kim Chang-Duck
Ryu Ho-Sang
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Abstract
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There is no established treatment for esophageal carcinoma with metastasis. For the metastatic esophageal squamous cell carcinoma, chemotherapy or best supportive care according to patient’s performance status are accepted as an available treatment. We report a case of complete remission after concurrent chemoradiotherapy for esophageal squamous cell carcinoma with metastatic lesion in 5th thoracic vertebrae. A 57-year-old man with ongoing dysphagia and weight loss was admitted to our hospital. On the endoscopic and radiologic imaging evaluation,the patient was diagnosed as a squamous cell carcinoma of esophagus with solitary metastatic lesion in 5th thoracic vertebrae. The patient was treated with combination chemotherapy (5-fluorouracil (5-FU) and cisplatin) and concurrent radiotherapy for two months to relieve dysphagia. Because metastatic lesion in thoracic vertebrae was located near the primary esophageal tumor, the metastatic lesion could be included within the radiation field. After concurrent chemoradiotherapy, consecutive 4 cycles of chemotherapy had been carried out. Primary esophageal tumor with metastatic lymph nodes and metastatic lesion in 5th thoracic vertebrae disappeared on follow up computed tomography (CT) and positron emission tomography-CT (PET-CT). Follow up endoscopic biopsy revealed no remnant malignant cells at previous primary cancer lesion.
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KEYWORD
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Esophagus, Carcinoma, Metastatsis, Concurrent, Chemoradiotherapy
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