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KMID : 1104820130010020100
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Journal of Digestive Cancer Research
2013 Volume.1 No. 2 p.100 ~ p.103
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Clinical Course and Side Effects of Imatinib in Recurrent Patient after Surgical Resection of GIST - A Case and Literature Review
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Bae Jung-Ho
Kim Gwang-Ha
Kim Dong-Uk
Lee Bong-Eun
Song Geun-Am
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Abstract
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A 79-year-old man was diagnosed with gastrointestinal stromal tumor (GIST) of the gastric cardia. We performed proximal subtotal gastrectomy and started imatinib therapy as adjuvant treatment after surgery. Whole body skin rash with urticaria was onset on 10 days after imatinib treatment, and the patient decided to stop imatinib because of side effect. After 3 months, PET CT revealed GIST was recurred at spleen and abdominal lymph nodes, abdominal wall. The patient was then restarted on imatinib therapy. On follow-up imaging studies, the tumor almost disappeared, but both pleural effusion and pericardial effusion were found. In this paper, we describe a case of clinical course and side effects in recurred GIST after adjuvant imatinib mesylate treatment.
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KEYWORD
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GIST, Imatinib, Side effect
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