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KMID : 1104820140020020075
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Journal of Digestive Cancer Research
2014 Volume.2 No. 2 p.75 ~ p.77
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A Case of Metastatic Ampulla of Vater Cancer Treated with Chemotherapy Followed by Pylorus Preserving Pancreaticoduodenectomy
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Yoon Hae-Ryong
Chung Moon-Jae
Bang Seung-Min
Park Seung-Woo
Song Si-Young
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Abstract
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Ampulla of Vater (AOV) cancer is rare malignant tumor which arises within the vicinity of the AOV. Metastatic AOV adenocarcinoma has poor prognosis, with an overall survival rate at 2 years ranging from 5 to 10%. The Surveillance, Epidemiology and End Results Program of the National Cancer Institute indicated that lymph node metastasis was present in as many as half of patients which were associated with poor prognosis and liver was the second most common site of distant metastasis in AOV cancer. In this case report, we describe a case of complete resolution of AOV cancer, which was already spread to retroperitoneal lymph node and liver. The patient underwent gemcitabine plus cisplatin chemotherapy for palliative aim. After 12 month of chemotherapy, image study showed partial remission, so intraoperative radiofrequency ablation therapy and pylorus preserving pancreaticoduodenectomy was done. AOV cancer was completely resected and the patient was followed up without recurrence for 7 months.
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KEYWORD
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Metastatic ampulla of Vater cancer, Chemotherapy, Pylorus preserving pancreaticoduodenectomy, Radiofrequency ablation therapy
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