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KMID : 1104820150030010030
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Journal of Digestive Cancer Research
2015 Volume.3 No. 1 p.30 ~ p.34
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A Case of Palliative Chemotherapy of Advanced Gastric Cancer with Multiple Hepatic Metastasis
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Shin Hae-Jin
Jeong Hyun-Yong
Moon Hee-Seok
Sung Jae-Kyu
Kang Sun-Hyung
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Abstract
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We report a case of a 55-year-old man who diagnosed with advanced gastric cancer (AGC), with A review of the literature. A 55-year old man was transferred to our hospital for further evaluation and treatment after being diagnosed with adenocarcinoma through endoscopic biopsy during a regular health examination. An abdominal computed tomography (CT) showed AGC, stage IIA (T3N3M0), while an endoscopic examination showed AGC, Borrmann type 2. The patient is currently under observation after undergoing radical subtotal gastrectomy with gastroduodenostomy and subsequent administration of oral chemotherapeutic agents. As an abdominal CT response assessment performed after surgery revealed new metastasis to the liver, the patient received palliative chemotherapy as progressive disease was suspected. After receiving chemotherapy in the order of FOLFOX (5-fluorouracil (5-FU)) + Leucovorin +Oxaliplatin), FOLFIRI (5-FU+ Leucovorin + Irinotecan), EAP-II (Etoposide + Doxorubicin + Cisplatin), ELF (Etoposide + Leucovorin + 5-FU), TS-1 (Tegafur + Gimeracil) + Cisplatin, an abdominal CT response assessment showed progressive disease for which the regimen was altered to PFL (Paclitaxel + 5-FU + Leucovorin). The patient has currently completed his second cycle of chemotherapy and after an abdominal CT response assessment, further course of therapy will be decided.
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KEYWORD
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Advanced gastric cancer, Palliative chemotherapy
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