|
KMID : 1118520120090040339
|
|
Psychiatry Investigation
2012 Volume.9 No. 4 p.339 ~ p.346
|
|
|
Verbal and Visual Memory Impairments in Bipolar I and II Disorder
|
|
Ha Tae-Hyon
Kim Ji-Sun
Chang Jae-Seung
Oh Sung-Hee
Her Ju-Young
Cho Hyun-Sang
Park Tae-Sung
Shin Soon-Young
Ha Kyoo-Seob
|
|
|
Abstract
|
|
|
Objective: To compare verbal and visual memory performances between patients with bipolar I disorder (BD I) and patients with bipolar II disorder (BD II) and to determine whether memory deficits were mediated by impaired organizational strategies.
Methods: Performances on the Korean-California Verbal Learning Test (K-CVLT) and the Rey-Osterrieth Complex Figure Test (ROCF) in 37 patients with BD I, 46 patients with BD II and 42 healthy subjects were compared. Mediating effects of impaired organization strategies on poor delayed recall was tested by comparing direct and mediated models using multiple regression analysis.
Results: Both patients groups recalled fewer words and figure components and showed lower Semantic Clustering compared to controls. Verbal memory impairment was partly mediated by difficulties in Semantic Clustering in both subtypes, whereas the mediating effect of Organization deficit on the visual memory impairment was present only in BD I. In all mediated models, group differences in delayed recall remained significant.
Conclusion: Our findings suggest that memory impairment may be one of the fundamental cognitive deficits in bipolar disorders and that executive dysfunctions can exert an additional influence on memory impairments.
|
|
|
KEYWORD
|
|
|
Bipolar I disorder, Bipolar II disorder, Memory, Organization, Executive function, Path analysis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|