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KMID : 1118520190160050397
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Psychiatry Investigation
2019 Volume.16 No. 5 p.397 ~ p.402
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Examining Patterns of Polypharmacy in Bipolar Disorder: Findings from the REAP-BD, Korea
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Kim Ki-Won
Yang Hyun-Ju
Na Eui-Hyeon
Lee Ho-Seon
Jang Ok-Jin
Yoon Hyung-Jun
Oh Hong-Seok
Ham Byung-Joo
Park Seon-Cheol
Lin Shih-Ku
Tan Chay Hoon
Shinfuku Naotaka
Park Yong-Chon
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Abstract
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Based on Korean data from the Research on Asian Psychotropic Prescription Pattern for Bipolar Disorder, this study tried to present prescription patterns in biopolar disorder (BD) and its associated clinical features. Based on the information obtained from the study with structured questions, the tendency of prescription pattern was studied and analyzed. Polypharmacy was predominant, including simple polypharmacy in 51.1% and complex polypharmacy in 34.2% of patients. Subjects associated with simple or complex polypharmacy were significantly younger, had higher inpatient settings, a larger portion of onset with manic episode, a shorter duration of untreated illness, a shorter duration of current episode, were more overweight, used less antidepressants and used more anxiolytics. These findings can suggest higher polypharmacy rate in more severe BD and highlight the necessity of monitoring the weight of subjects with polypharmacy.
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KEYWORD
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Polypharmacy, Bipolar disorder, Inpatient, Antidepressant
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