KMID : 1120220110020030210
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Osong Public Health and Research Perspectives 2011 Volume.2 No. 3 p.210 ~ p.215
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Sensitivity Analysis of the Parameters of Korea¡¯s Pandemic Influenza Preparedness Plan
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Chu Chae-Shin
Lee June-Hawk Choi Dong-Hoon Youn Seung-Ki Lee Jong-Koo
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Abstract
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Objectives: Our aim was to evaluate Korea¡¯s Pandemic Influenza Preparedness Plan.
Methods: We conducted a sensitivity analysis on the expected number of outpatients and hospital bed occupancy, with 1,000,000 parameter combinations, in a situation of pandemic influenza, using the mathematical simulation program InfluSim.
Results: Given the available resources in Korea, antiviral treatment and social distancing must be combined to reduce the number of outpatients and hospitalizations sufficiently; any single intervention is not enough. The antiviral stockpile of 4?6% is sufficient for the expected eligible number of cases to be treated. However, the eligible number assumed (30% for severe cases and 26% for extremely severe cases) is very low compared to the corresponding number in European countries, where up to 90% of the population are assumed to be eligible for antiviral treatment.
Conclusions: A combination of antiviral treatment and social distancing can mitigate a pandemic, but will only bring it under control for the most optimistic parameter combinations.
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KEYWORD
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influenza pandemic, preparedness planning, sensitivity analysis
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