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KMID : 1120220120030030128
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Osong Public Health and Research Perspectives
2012 Volume.3 No. 3 p.128 ~ p.136
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Optimal Control Strategy of Plasmodium vivax Malaria Transmission in Korea
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Kim Byul-Nim
Nah Kyeong-Ah
Chu Chae-Shin
Ryu Sang-Uk
Kang Yong-Han
Kim Yong-Kuk
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Abstract
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Objective: To investigate the optimal control strategy for Plasmodium vivax malaria transmission in Korea.
Methods: A Plasmodium vivax malaria transmission model with optimal control terms using a deterministic system of differential equations is presented, and analyzed mathematically and numerically.
Results: If the cost of reducing the reproduction rate of the mosquito population is more than that of prevention measures to minimize mosquito-human contacts, the control of mosquito-human contacts needs to be taken for a longer time, comparing the other situations. More knowledge about the actual effectiveness and costs of control intervention measures would give more realistic control strategies.
Conclusion: Mathematical model and numerical simulations suggest that the use of mosquito-reduction strategies is more effective than personal protection in some cases but not always.
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KEYWORD
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epidemiological model, malaria, numerical simulation, optimal control
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