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KMID : 1120220170080040282
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Osong Public Health and Research Perspectives
2017 Volume.8 No. 4 p.282 ~ p.288
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Seroprevalence of Brucellosis in Human Immunodeficiency Virus Infected Patients in Hamadan, Iran
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Keramat Fariba
Majzobi Mohammad Mehdi
Poorolajal Jalal
Ghane Zohreh Zarei
Adabi Maryam
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Abstract
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Objectives: Brucellosis is a systemic disease with a wide spectrum of clinical manifestations. This study aimed to determine the seroprevalence of brucellosis in human immunodeficiency virus (HIV) infected patients in Hamadan Province in the west of Iran.
Methods: A total of 157 HIV-infected patients were screened through standard serological tests, including Wright’s test, Coombs’ Wright test, and 2-mercaptoethanol Brucella agglutination test (2ME test), blood cultures in Castaneda media, and CD4 counting. Data were analyzed using Stata version 11.
Results: Wright and Coombs’ Wright tests were carried out, and only 5 (3.2%) patients had positive serological results. However, all patients had negative 2ME results, and blood cultures were negative for Brucella spp. Moreover, patients with positive serology and a mean CD4 count of 355.8 ± 203.11 cells/μL had no clinical manifestations of brucellosis, and, and the other patients had a mean CD4 count of 335.55 ± 261.71 cells/μL.
Conclusion: Results of this study showed that HIV infection is not a predisposing factor of acquiring brucellosis.
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KEYWORD
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brucellosis, human immunodeficiency virus, serology
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