KMID : 1120220210120010037
|
|
Osong Public Health and Research Perspectives 2021 Volume.12 No. 1 p.37 ~ p.43
|
|
Genomic Surveillance of SARS-CoV-2: Distribution of Clades in the Republic of Korea in 2020
|
|
Park Ae-Kyung
Kim Il-Hwan Kim Jun-Young Kim Jeong-Min Kim Heui-Man Lee Chae-Young Han Myung-Guk Rhie Gi-Eun Kwon Dong-Hyok Nam Jeong-Gu Park Young-Joon Gwack Jin Lee Nam-Joo Woo Sang-Hee No Jin-Sun Lee Jae-Hee Ha Jee-Min Rhee Jee-Eun Yoo Cheon-Kwon Kim Eun-Jin
|
|
Abstract
|
|
|
Since a novel beta-coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019, there has been a rapid global spread of the virus. Genomic surveillance was conducted on samples isolated from infected individuals to monitor the spread of genetic variants of SARS-CoV-2 in Korea. The Korea Disease Control and Prevention Agency performed whole genome sequencing of SARS-CoV-2 in Korea for 1 year (January 2020 to January 2021). A total of 2,488 SARS-CoV-2 cases were sequenced (including 648 cases from abroad). Initially, the prevalent clades of SARS-CoV-2 were the S and V clades, however, by March 2020, GH clade was the most dominant. Only international travelers were identified as having G or GR clades, and since the first variant 501Y.V1 was identified (from a traveler from the United Kingdom on December 22nd, 2020), a total of 27 variants of 501Y.V1, 501Y.V2, and 484K.V2 have been classified (as of January 25th, 2021). The results in this study indicated that quarantining of travelers entering Korea successfully prevented dissemination of the SARS-CoV-2 variants in Korea.
|
|
KEYWORD
|
|
SARS-CoV-2, whole-genome sequencing, Republic of Korea
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|