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KMID : 1120220230140040291
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Osong Public Health and Research Perspectives
2023 Volume.14 No. 4 p.291 ~ p.299
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Prevalence and patterns of adverse events following childhood immunization and the responses of mothers in Ile-Ife, South West Nigeria: a facility-based cross-sectional survey
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Olorunfemi Akinbode Ogundele
Funmito Omolola Fehintola
Mubarak Salami
Rahmat Usidebhofoh
Mary Aderemi Abaekere
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Abstract
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Objectives : This study aimed to examine the prevalence and pattern of adverse events following childhood immunization and the responses of mothers in Ile-Ife, South West Nigeria.
Methods : This descriptive cross-sectional study was conducted among 422 mothers of children aged 0 to 24 months attending any of the 3 leading immunization clinics in Ile-Ife, Nigeria. The respondents were selected using the multi-stage sampling technique. Data were collected using a pretested structured interviewer-administered questionnaire and analyzed using IBM SPSS ver. 26.0. The chi-square test was used to test associations, while binary logistic regression was used to determine the predictors of mothers' responses to adverse events following immunization (AEFIs). A p-value of <0.05 was considered statistically significant.
Results : The mean age of the respondents was 29.99±5.74 years. About 38% of the children had experienced an AEFI. Most mothers believed that the pentavalent vaccine was the most common cause of AEFIs (67.5%). Fever (88.0%) and pain and swelling (76.0%) were the most common AEFIs. More than half of the mothers (53.7%) administered home treatment following an AEFI. Younger mothers (odds ratio [OR], 2.43; 95% confidence interval [CI], 1.20?5.01), mothers who delivered their children at a healthcare facility (OR, 3.24; 95% CI, 1.08?9.69), and mothers who were knowledgeable about reporting AEFIs (OR, 2.53; 95% CI, 1.04?7.70) were most likely to respond appropriately to AEFIs.
Conclusion : The proportion of mothers who responded poorly to AEFIs experienced by their children was significant. Therefore, strategies should be implemented to improve mothers’ knowledge about AEFIs to improve their responses.
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KEYWORD
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Adverse events, Child, Immunization, Nigeria, Prevalence, Vaccines
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