KMID : 1132720130110010052
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Genomics & Informatics 2013 Volume.11 No. 1 p.52 ~ p.54
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Eukaryotic DNAJ/K Database: A Comprehensive Phylogenomic Analysis Platform for the DNAJ/K Family
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Cheong Kyeong-Chae
Choi Jae-Hyuk Choi Jae-Young Park Jong-Sun Jang Su-Wang Lee Yong-Hwan
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Abstract
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Proteins in DNAJ/K families are ubiquitous, from prokaryotes to eukaryotes, and function as molecular chaperones. For systematic phylogenomics of the DNAJ/K families, we developed the Eukaryotic DNAJ/K Database (EDD). A total of 12,908 DNAJs and 4,886 DNAKs were identified from 339 eukaryotic genomes in the EDD. Kingdom-wide comparison of DNAJ/K families provides new insights on the evolutionary relationship within these families. Empowered by ¡¯class¡¯, ¡¯cluster¡¯, and ¡¯taxonomy¡¯ browsers and the ¡¯favorite¡¯ function, the EDD provides a versatile platform for comparative genomic analyses of DNAJ/K families.
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KEYWORD
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database, HSP40 heat-shock proteins, HSP70 heat-shock proteins
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FullTexts / Linksout information
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