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KMID : 1134120110140000031
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Journal of Breast Cancer
2011 Volume.14 No. 0 p.31 ~ p.36
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Serum Level Change of Follicle Stimulating Hormone in Menopausal Women with Breast Cancer according to Age in Korea
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Lee On-Vox
Son Byung-Ho
Lee Jong-Won
Kim Hee-Jung
Ko Beom-Seok
Yu Jong-Han
Lee Yu-Mi
Kwon Soo-Bum
Shin En-Jung
Ahn Sei-Hyun
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Abstract
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Purpose: The aim of this study is to evaluate the relationship of menopause and serum follicle stimulating hormone (FSH) level and estradiol (E2) in Korean women with breast cancer.
Methods: We reviewed 1,404 women aged from 20- to 82-year-old (median 47 years) with breast cancer who had got surgery at Asan Medical Center in 2008. All patients were checked serum FSH before the operation. Three hundred fifty-three patients were in postmenopause state at the time of surgery. Their ages were from 40- to 60-year-old (median 50.3 years).
Results: The proportion of postmenopausal status in each age-group were 5.1% (45- to 49-year-old), 41% (50- to 54-year-old), 86.1% (55- to 59-year-old), and 100% over the age of 60, respectively. And the proportion of the patients with FSH over 30 mUI/mL were 68.6% (45-to 49-year-old), 87.5% (55- to 59-year-old), 75.0% (55- to 59-year-old) and 30.0% (over the age of 60), respectively
Conclusion: Our study shows that even though patients had been in amenorrhea over 1 year, not all patients have their FSH level over 30 mUI/mL. And this finding is more prominent in age group from 45- to 49-year-old.
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KEYWORD
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Breast neoplasms, Follicle stimulating hormone, Menopause
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