KMID : 1134820150440020287
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Journal of the Korean Society of Food Science and Nutrition 2015 Volume.44 No. 2 p.287 ~ p.290
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Detection of Antifungal Activities from Pomegranate
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Lee Geum-Young
Park Tae-Hee Lee Da-In Park Jeong-Ro Choi Sang-Ki
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Abstract
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Antifungal activities of pomegranate were investigated. Seventy percent ethanol extracts of seeds, peels, and whole fruits of pomegranate showed similar antifungal activities against Candida albicans in liquid media, whereas extract of whole fruit showed relatively high antifungal activity in solid media. When 70% ethanol extracts were fractionated sequentially with chloroform and ethyl acetate, ethyl acetate fraction exhibited the highest anti-fungal activities against C. albicans. Ethyl acetate fractions of whole fruits and peel portions showed at least 36% and 25% growth against C. albicans, Candida glabrata, Candida tropicalis, and Candida lusitaniae in liquid media, respectively. These results indicate that pomegranate contains antifungal compounds soluble with organic solvents.
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KEYWORD
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pomegranate, antifungal activity, Candida albicans, growth inhibition
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