KMID : 1134820190480010018
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Journal of the Korean Society of Food Science and Nutrition 2019 Volume.48 No. 1 p.18 ~ p.23
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Effects of Lamb Placenta on UVB-Induced Decrease in Skin Hydration
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Park Soo-Jeung
Lee Min-Hee Yun Jeong-Moon Kim Da-Kyung Kim Ok-Kyung
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Abstract
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We investigated the potential effects of lamb placenta on UVB irradiation-induced decreases in skin hydration in vitro and in vivo. We found that UVB irradiation suppressed the mRNAs expression of procollagen type ¥°, collagen type ¥°, elastin, fibrillin-1, and hyaluronan synthase 2 in back skin from UVB-irradiated hairless mice. In addition, UVB irradiation decreased the skin hydration in hairless mice. However, dietary supplement of lamb placenta inhibited the decreases in the mRNAs expression of procollagen type ¥°, collagen type ¥°, elastin, fibrillin-1, and hyaluronan synthase 2 and the skin hydration in UVB-irradiated hairless mice. Moreover, we found that lamb placenta treatment increased hyaluronan production while UVB irradiation decreased hyaluronan production in UVB-irradiated HaCaT cells. Therefore, these results confirmed the possibility that lamb placenta could be developed as a functional food material to increase skin moisturizing.
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KEYWORD
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lamb placenta, UVB, skin aging, skin hydration
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