|
KMID : 1140320170010040159
|
|
Precision and Future Medicine
2017 Volume.1 No. 4 p.159 ~ p.167
|
|
|
Old drug, new findings: colistin resistance and dependence of Acinetobacter baumannii
|
|
Ko Kwan-Soo
Choi Yu-Jin
Lee Ji-Young
|
|
|
Abstract
|
|
|
|
Colistin is an old drug, and its use has recently resurged because of increasing antibiotic resistance in gram-negative bacteria such as Acinetobacter baumannii. Although the colistin resistance rates in gram-negative bacteria are currently not high, many colistin-resistant isolates are being identified and the possibility of horizontal transmission of colistin resistance has increased because of the plasmid-borne colistin resistance gene mcr-1 (mobilized colistin resistance). In this review, we have discussed colistin resistance in A. baumannii. In addition, we have reviewed an abnormal phenomenon called colistin dependence in A. baumannii.
|
|
|
KEYWORD
|
|
|
Gram-negative bacteria, PmrAB, Polymyxins
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|