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KMID : 1140320210050020069
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Precision and Future Medicine
2021 Volume.5 No. 2 p.69 ~ p.76
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Strategies for colorectal cancer screening and post-polypectomy surveillance for young adults under age 50
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Jung Yoon-Suk
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Abstract
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The incidence of colorectal cancer in young adults aged < 50 years is increasing. In line with these recent trends, it is necessary to pay attention to young-onset colorectal adenoma, a precursor of colorectal cancer. Recent studies have reported that the prevalence of colorectal adenomas in young adults aged < 50 years is not low. Moreover, it has been reported that the prevalence of advanced colorectal neoplasia (advanced adenoma or colorectal cancer) in young persons aged < 50 years with clinical risk factors or a positive fecal immunochemical test result is not lower than that in average-risk older persons. In this review, I examined and summarized the prevalence and risk factors of colorectal neoplasia (colorectal adenoma or colorectal cancer) in young adults aged < 50 years. Considering the results of previous studies, I proposed effective strategies for colorectal cancer screening using clinical risk factors and the fecal immunochemical test, and discussed post-polypectomy surveillance for this age group.
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KEYWORD
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Colorectal neoplasms, Young adults
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