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KMID : 1141120180040020115
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The Nerve
2018 Volume.4 No. 2 p.115 ~ p.119
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Idiopathic Granulomatous Hypophysitis: A Case Report and Literature Review
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Eom Tae-Oong
Park Eun-Suk
Park Sung-Ho
Kim Min-Soo
Kwon Soon-Chan
Sim Hong-Bo
Lyo In-Uk
Park Jun-Bum
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Abstract
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Idiopathic granulomatous hypophysitis (IGH) is a rare inflammatory disorder of the pituitary that causes transient or permanent gland dysfunction and various neurological symptoms. We present a case involving a 24-year-old woman who was admitted for headache and visual disturbance. The patient was preoperatively diagnosed with pituitary adenoma and underwent transsphenoidal surgery. Histopathology revealed a diagnosis of granulomatous hypophysitis. She was finally diagnosed with IGH given the absence of systemic granulomatous disease. Because IGH is a rare disease and is easily misdiagnosed as other pituitary disease, careful inspection of patient symptoms is required. Surgical intervention provides a histological diagnosis and immediate mass reduction in patients with IGH; however, hormone replacement is frequently required, and long-term follow up is very important.
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KEYWORD
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Hypophysitis, Pituitary diseases, Pituitary gland, Sella turcica
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