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KMID : 1141120200060020050
The Nerve
2020 Volume.6 No. 2 p.50 ~ p.56
Postoperative Delirium after Spine Surgery: A Single-Center Age-Matched Study
Lee Jae-Cheol

Bae Young-Oh
Shin Hyun-Chul
Kwon Young-Joon
Abstract
Objective: Postoperative delirium is a common disorder after surgery in the older population leading to difficulty in the postoperative period. However, there are currently insufficient understanding and few studies on postoperative delirium in spine surgery. The purpose of the present study was to evaluate the incidence and risk factors leading to postoperative delirium after spine surgery in an age-matched cohort.

Method: This study retrospectively reviewed the incidence of delirium in 3,581 patients who underwent spine surgery from 2005 to 2019 at a single institution. The authors reviewed the patient history for unmodifiable and modifiable factors in the past, pre- and postoperative blood lab results, and intraoperative factors.

Results: Each patient in the delirium group was age-matched with two patients in the delirium-negative group with the allocated propensity score (1:2). Overall incidence rate of postoperative delirium was 3.07% (110/3,581). The incidence of postoperative delirium increased with increasing age. Multivariate analysis shows that smoking history (p=0.008), the use of psychiatric medication (p=0.004), the use of steroids (p=0.041), preoperative C-reactive protein (CRP; p=0.001), blood chloride (Cl) levels (p=0.006), fasting blood glucose levels (p=0.004), Intraoperative transfusions (p=0.044), and postoperative CRP (p=0.040), erythrocyte sedimentation rate (p¡Â0.001), and blood Cl levels (p=0.005) were identified as significant risk factors for postoperative delirium.

Conclusion: It is important to recognize and check the significant risk factors of postoperative delirium after spine surgery. Dedicated perioperative care should be performed to prevent postoperative delirium in patients with the risk factors.
KEYWORD
Delirium, Matched-pair analysis, Risk factors, Spine, Surgery
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