|
KMID : 1141720140020020001
|
|
폐쇄성폐질환
2014 Volume.2 No. 2 p.1 ~ p.1
|
|
|
|
|
Rhee Chin-Kook
Moon Ji-Yong
Ra Seung-Won
Park Yong-Bum
|
|
|
Abstract
|
|
|
|
Asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) is characterized by persistent airflow limitation with several features usually associated with asthma and several features usually associated with COPD. ACOS is therefore identified by the features that it shares with both asthma and COPD. A significant proportion of patients who present with symptoms of a chronic airways disease have features of both asthma and COPD. Patients with ACOS have the combined risk factors of smoking and atopy and experience acute exacerbations with higher frequency and greater severity than lone COPD. Pharmacotherapeutic considerations require an integrated approach, first to identify the relevant clinical phenotypes, then to determine the best available therapy. A consensus international definition of ACOS is needed to design prospective, randomized clinical trials to evaluate specific drug interventions.
|
|
|
KEYWORD
|
|
|
Asthma, Asthma-COPD overlap syndrome, Chronic obstructive pulmonary disease
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|