|
KMID : 1141720160040020008
|
|
폐쇄성폐질환
2016 Volume.4 No. 2 p.8 ~ p.8
|
|
|
|
|
Kim Je-Hyeong
|
|
|
Abstract
|
|
|
|
Chronic obstructive pulmonary disease (COPD) is characterized by hyperinflation of lung, general atrophy of inspiratory muscles, and presence of intrinsic positive end-expiratory pressure due to airway obstruction, resulting in increase in respiratory threshold and workload. In these conditions, noninvasive ventilation (NIV) using positive pressure can decrease load to respiratory muscles and respiratory workload, improve efficiency of alveolar ventilation and degree of dyspnea. In spite of lack of concrete evidence, NIV potentially improves quality of life, prolongs survival, and improves gas exchange and sleep quality. Especially, NIV is effective in patients with arterial carbon dioxide levels greater than 55 mmHg, or nocturnal hypoventilation and arterial carbon dioxide levels between 50 and 54 mmHg, and frequent hospitalization. Therefore, long-term home ventilation with NIV can be considered in severe stable COPD patients with hypercapnic respiratory failure in spite of optimal medical therapy.
|
|
|
KEYWORD
|
|
|
Chronic obstructive pulmonary disease, Noninvasive ventilation
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|